![]() In this study, we introduced maleimidopropionic acid (MPA) to a PSMA-targeted tracer and developed Al 18F-PSMA-CM, which targets human serum albumin (HSA) binding and PSMA. Improving the circulation of radioligands in the blood is considered as an effective strategy that can improve tumor burden, which benefits detection of small lesions and improves the effect of PSMA radioligand therapy (PRLT). Prostate-specific membrane antigen (PSMA) is an attractive target for the diagnosis and therapy of prostate cancer as it is specifically overexpressed in prostate cancer cells. 2Guizhou University School of Medicine, Guizhou University, Guiyang, China. ![]() ![]()
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